Bedaquiline Manufacturers and Suppliers in India
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- Name of the product: Bedaquiline Fumarate
- Molecular weight: 525.49
- Formula: C32H31BrN2O2
- Usage: Pharmaceuticals
- Form: Crystalline powder
- Color: White
- Size of package: As per requirement
Chemical properties:
It is a white to off-white crystalline powder with low solubility in water
Applications:
Bedaquiline fumarate, an antituberculosis drug, works by binding to the adenosine triphosphate (ATP) synthase enzyme in mycobacteria, which prevents the production of ATP.
India is rolling out BPal shortened treatment regime. BPal, the new treatment regime involves use of three medicines—Bedaquiline, Pretomanid and Linezolid—with 89 percent success rate within six months. The standard care, on the other hand, takes 18 months with a 52 percent success rate.
Bedaquiline fumarate is classified under the Biopharmaceutical Classification System (BCS) as a Class II compound. This classification is based on its properties
Benefits:
Solubility: Bedaquiline has low aqueous solubility.
Permeability:It exhibits high permeability across biological membranes.
Class II drugs are characterized by their poor solubility but good permeability, which can impact their absorption and bioavailability.
